Windsor FC start their Combined Counties Premier Division campaign on Saturday but boss Keith Scott is facing a selection headache.
New signing James Houghton fractured his wrist in the 2-2 draw with Holyport on Thursday night and will be in a cast for the next six weeks.
And striker Leeyon Phelan could be set for an extended spell on the sidelines after picking up a knee injury in Windsor's final friendly of the summer against Hayes & Yeading on Saturday.
Kyle Anthony has a hernia so his playing time will have to be managed until he can have an operation while Joe Chandiram and Yash Romeo are on holiday.
Scott admits his squad has been pushed to the limit in recent days but he insists he will not be using that as an excuse come 3pm on Saturday when Windsor host Epsom & Ewell in their league opener.
He said: "I'm happy with where we are but we've picked up a couple of injuries in the last week which we could do without.
"James (Houghton) fractured his wrist against Holyport and he will be out for at least six weeks. I'm disappointed for him more than anything.
He is a player we looked at last season and he's done fantastically well since coming here. It's a real blow as he's probably our most natural box to box midfielder."
The Windsor boss added: "Leeyon (Phelan) hyper-extended his knee against Hayes and needs an MRI scan. It could be pretty serious.
"And Kyle Anthony has a hernia and needs an operation. He can still play with it, it all just depends on his pain threshold.
"We also have Yash and Joe on holiday so we're going into the first game a little bit light.
"Fate has gone against us a bit on the last week or so but we'll just have to go with what we've got."
Windsor begin their season at home to Epsom & Ewell on Saturday before visiting Bedfont Sports on Tuesday night.
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